Alnylam

February 8, 2012

The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals

Moon et al., Cell Metabolism. 2012 Feb 8; 15:240-6

February 2, 2012

A rapid two-step method for isolation of functional primary mouse hepatocytes: cell characterization and asialoglycoprotein receptor based assay development

Severgnini et al, Cytotechnology. 2011 Nov 22 (Epub)

January 31, 2012

Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo

D. Foster et al., RNA. 2012 Jan 31. (Epub)

January 30, 2012

IRE1-alpha activation protects mice against acetaminophen-induced hepatotoxicity.

Hur et al, J Exp Med. 2012 Jan 30 (Epub)

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November 22, 2011

Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells

T. Novobrantseva et al., Mol Ther-Nucleic Acids. 2012 Jan 24; 1, e4

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November 11, 2011

Widespread suppression of huntingtin with convection-enhanced delivery of siRNA

D.K. Stiles et al., Exp Neuro. 2011 (Epub 2011 Nov 11) Continue reading…

October 9, 2011

Therapeutic siRNA silencing in inflammatory monocytes in mice

F. Leuschner et al., Nature Biotech. 2011 10.1038/nbt.1989. Epub 2011 Oct 09.

October 4, 2011

Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells (APCs)

Basha et al., Molecular Therapy, 2011, doi:10.1038/mt.2011.190. Epub 2011 October 04

July 22, 2011

Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

DJ Siegwart et al., Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):12996-3001. Epub 2011 Jul 22.

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June 18, 2011

Synergistic Silencing: Combinations of Lipid-like Materials for Efficacious siRNA Delivery

K.A. Whitehead et. al, Mol Therapy. 2011 Jul 12. doi: 10.1038/mt2011.141. Epub 2011 Jun 18.

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The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals

A rapid two-step method for isolation of functional primary mouse hepatocytes: cell characterization and asialoglycoprotein receptor based assay development

Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo

IRE1-alpha activation protects mice against acetaminophen-induced hepatotoxicity.

Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells

Widespread suppression of huntingtin with convection-enhanced delivery of siRNA

Therapeutic siRNA silencing in inflammatory monocytes in mice

Influence of Cationic Lipid Composition on Gene Silencing Properties of Lipid Nanoparticle Formulations of siRNA in Antigen-Presenting Cells (APCs)

Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery

Continue reading…

Synergistic Silencing: Combinations of Lipid-like Materials for Efficacious siRNA Delivery

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