Our scientists presented an update on our RNAi delivery strategies at the AsiaTIDES conference this week. The presentation focuses on our recent progress utilizing conjugates and lipid nanoparticles for systemic adminstration of RNAi therapeutics.
View our presentation (2.4MB PDF)Posts Tagged with: Leadership in RNAi
February 9, 2012
Novel Method for Monitoring RNAi Activity in Blood Samples
Our scientists discovered a new method for monitoring RNAi activity in blood samples. The results were presented at the Keystone Gene Silencing by small RNAs symposium (Vancouver, February 7-12). This new method, circulating extracellular RNA detection (cERD), allows quantitative measurement of tissue-specific mRNA silencing from biological fluids including blood and cerebrospinal fluid (CSF).
View our poster (1.18 MB PDF) Read our press releaseJanuary 31, 2012
Comprehensive evaluation of canonical versus Dicer-substrate siRNA in vitro and in vivo
November 9, 2011
Illustrating our VaxiRNA Platform
In early November, we launched our VaxiRNA™ platform as a result of research performed by our Alnylam Biotherapeutics team. VaxiRNA uses siRNA to silence specific genes that limit or prevent effective growth of viruses in vaccine manufacturing systems, including those in cell culture and also in chicken eggs.
View Illustration (2.28MB PDF) Read our press releaseOctober 11, 2011
New Alnylam Papers on Systemic Delivery of RNAi Therapeutics
We published two peer-reviewed papers in top-tier journals documenting the systemic delivery of RNAi therapeutics to certain immune and inflammatory cells. The findings from these studies provide us with the opportunity to explore RNAi therapeutic approaches to silence genes involved in inflammatory, autoimmune, and cardiovascular diseases, as well as certain cancers.
Read our press release Nature Biotechnology articleJune 18, 2011
Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter.
July 8, 2010
A status report on RNAi therapeutics.
January 17, 2010
Rational design of cationic lipids for siRNA delivery.
January 11, 2010
