Capella

Posts Tagged with: Respiratory Syncytial Virus

September 4, 2012

Complete Results of our ALN-RSV01 Phase IIb Study

At the European Respiratory Society’s (ERS) Annual Congress held in Vienna September 1-5, 2012, we presented complete results from our Phase IIb trial with ALN-RSV01 for the treatment of respiratory syncytial virus (RSV) infection in lung transplant patients… Continue reading…

May 29, 2012

Top-line Results of our Phase IIb Study of ALN-RSV01

We reported top-line results from our Phase IIb trial with ALN-RSV01 for the treatment of respiratory syncytial virus (RSV) infection in lung transplant patients.  The primary endpoint of the study was the incidence of new or progressive bronchiolitis obliterans syndrome (BOS) at 180 days after RSV infection. 

Read our press  release Listen to our discussion of the top-line results View our  presentation (449 KB PDF) View additional ALN-RSV program materials

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January 1, 2012

ALN-RSV Historical Press Releases

For your convenience we have collected a list of historical releases that cover the historical progress of our clinical program for respiratory syncitial virus*

2012

30/05/2012Alnylam Announces Top-Line Results of Phase IIb Clinical Trial

2011

29/11/2011Alnylam Completes Enrollment in Phase IIb Study

2010

29/09/2010 Alnylam Publishes Results from Phase IIa 27/04/2010 Alnylam Publishes Results from Phase II GEMINI Trial with ALN-RSV01 22/02/2010  Alnylam Initiates Phase IIb Clinical Trial of ALN-RSV01

2009

20/07/2009  Alnylam and Cubist Announce Complete Data from Phase II Study 08/06/2009  Alnylam to Webcast Conference Call to Discuss Preliminary Data from Phase II 08/06/2009  Alnylam and Cubist Report Preliminary Data from Phase II Study of ALN-RSV01 09/01/2009  Alnylam and Cubist Form Strategic Collaboration

2008

19/06/2008  Alnylam and Kyowa Hakko Form Alliance 09/04/2008  Alnylam Initiates Phase II Trial to Evaluate Safety and Tolerability 25/02/2008  Alnylam to Webcast Conference Call to Discuss Phase II GEMINI Data for ALN-RSV01 23/01/2008  Alnylam Reports Positive Phase II Data for ALN-RSV01

2007

13/12/2007  Alnylam Reports Continued Progress in Clinical Development of ALN-RSV01 26/06/2007  Alnylam Initiates Phase II Clinical Trial

2006

28/11/2006  Alnylam Initiates Clinical Program to Evaluate Anti-Viral Activity for ALN-RSV01 11/10/2006  Alnylam Initiates Phase I Clinical Study of Inhaled Formulation of ALN-RSV01 30/04/2006  Alnylam Reports Phase I Clinical Safety Data for ALN-RSV01 25/04/2006  Alnylam to Present Phase I Data for ALN-RSV01, an RNAi Therapeutic for the Treatment of RSV

 

November 10, 2010

Viral load drives disease in humans experimentally infected with respiratory syncytial virus

J. DeVincenzo Am J Respir Crit Care Med. 2010 Nov 15;182(10):1305-14. Epub 2010 Jul 9.

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April 26, 2010

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus.

J. DiVincenzo et. al, Proc Natl Acad Sci U S A. 2010 May 11;107(19):8800-5. Epub 2010 Apr 26.

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July 30, 2009

Alnylam RNAi Roundtable: ALN-RSV Program

In July 2009, we held an RNAi Roundtable focused on our ALN-RSV program. 

ALN-RSV RNAi Roundtable, July 2009 (1.3MB PPT)

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June 8, 2009

RNA interference-mediated silencing of the respiratory syncytial virus nucleocapsid defines a potent antiviral strategy.

R. Alvarez et. al, Antimicrob Agents Chemother. 2009 Sep;53(9):3952-62. Epub 2009 Jun 8.

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December 26, 2007

Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV).

J. DeVincenzo et. al, Antiviral Res. 2008 Mar;77(3):225-31. Epub 2007 Dec 26.

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This part of our website contains archived information which should not be considered current and may no longer be accurate.