/*--------------investigator-initiated-studies---------------*/
.paragraph-id--200 .description--component {
  padding-top: 0px;
}
/******************diversity-inclusion-page*****************/
.paragraph-id--154 .description--component {
  padding-bottom: 64px;
}
/*********************************************************/
.description--component .col-sm-4 h2 {
  font-size: 45px;
  color: #003366;
  font-weight: 600;
  line-height: 1.1em;
  text-transform: uppercase;
  margin: 0;
}
.description--component .col-sm-4 h3 {
  font-size: 35px;
  font-weight: 300;
  color: #003366;
}
.description--component .col-sm-4 p {
  font-weight: 400;
  font-size: 17px;
}

.paragraph--type--sim img {
  width: 100%;
  height: auto;
}
.description--component .row.text-center .col-sm-3 p.image-title {
  color: #003366;
  font-weight: 600;
  line-height: 1.2;
  margin-bottom: 1.2rem;
  margin-top: 13px;
}
.description--component .content.overlap {
  border-bottom: 6px solid #003366;
  min-height: 565px;
  margin-left: -92px;
  background: #fff;
  margin-top: 39px;
  padding: 64px 40px 64px 96px;
  box-shadow: 0 0 4px #ddd;
}
/* ----------------------Eligiblity field--------------- */
.description--component ul {
  margin: 32px 0px 30px;
}
.description--component ul li {
  margin-bottom: 16px;
}
.description--component ul li::marker {
  color: #ff9900;
}
.description--component ul li a {
  font-weight: 900;
}
.page-node-46 .html-content-background {
  margin-bottom: 64px;
}
/* ------------------------------------------------ HTML WITH BACKGROUND -------------------------------------*/
.html-content-background {
  margin: auto;
  padding: 64px 48px;
}
.html-content-background h4 {
  text-align: center;
  margin-top: 10px;
  font-size: 35px;
  font-weight: 300;
  color: #003366;
  line-height: 1.1em;
  padding-bottom: 24px !important;
  margin-bottom: 0 !important;
}
.html-content-background h1 {
  margin-bottom: 16px !important;
}
.html-content-background text {
  font-weight: 400;
  font-size: 17px;
  line-height: 24px;
  color: #818181;
  margin-bottom: 32px !important;
  display: block;
}

.html-content-background .description--component ol li p {
  font-size: 14px !important;
  margin-bottom: 0px !important;
  font-weight: normal !important;
}
.html-content-background .description--component ol li::marker {
  font-weight: bold;
}

.html-content-background .row .col-sm-6 ul li::marker {
  color: #ff9900;
}

.html-content-background .row.inner-block {
  display: contents;
}

.html-content-background .description--component h3 {
  color: #003366;
  font-size: 23px;
  font-weight: 600;
  line-height: 24px;
  letter-spacing: 0;
}
.html-content-background .description--component {
  padding: 0px;
}

/* --------------------------------Full Html content with background--------------------- */

#full-html-content-background {
  padding: 64px 0px;
  margin-bottom: 64px;
}

#full-html-content-background h4 {
  text-align: center;
  margin-top: 10px;
  font-size: 35px;
  font-weight: 300;
  color: #003366;
  line-height: 1.1em;
  padding-bottom: 24px !important;
  margin-bottom: 0 !important;
}
#full-html-content-background text {
  font-weight: 400;
  font-size: 17px;
  line-height: 24px;
  color: #818181;
  margin-bottom: 20px !important;
  display: block;
}

#full-html-content-background p {
  font-weight: 400;
  font-size: 17px;
  line-height: 24px;
  color: #333333;
}
#full-html-content-background p.text-align-center {
  font-weight: 400;
  font-size: 17px;
  line-height: 24px;
  color: #333333;
  padding: 0 32px;
}
#full-html-content-background a {
  border-bottom: 1.5px solid #b9d9eb;
  font-weight:900;
}
#full-html-content-background .description--component #genetic-testing p.bottom-text a {
  border-bottom: 1.5px solid #b9d9eb;
  font-weight:900;
}
.paragraph-id--399 #full-html-content-background .description--component #genetic-testing p.bottom-text{
   font-weight:700;
}
#full-html-content-background ul li::marker {
  color: #ff9900;
}

#full-html-content-background .row.inner-block {
  padding: 0px 60px;
}

#full-html-content-background .description--component h3 {
  color: #003366;
  font-size: 23px;
}
#full-html-content-background .description--component {
  padding: 0px;
}
/* ---------------------- HTML content background advocacy bottom grid ---------------------- */

.html-content-background .advocacy-bottom-grid {
  text-align: center;
}

.html-content-background .advocacy-bottom-grid .col-sm-3 {
  background: #ffffff;
  width: 22.9%;
  padding: 40px 32px;
  margin-right: 30px;
  min-height: 592px;
}

.html-content-background .advocacy-bottom-grid .col-sm-3:nth-child(4) {
  margin-right: 0px;
}

.html-content-background .advocacy-bottom-grid h4 {
  font-size: 35px;
  font-weight: 300;
  color: #003366;
  line-height: 1.1em;
  padding-bottom: 6px;
}

.html-content-background .advocacy-bottom-grid text {
  font-size: 20px;
  line-height: 30px;
  font-weight: 400;
}

.html-content-background .advocacy-bottom-grid .grid-img img {
  width: 96px;
  margin-bottom: 24px;
}

.html-content-background .advocacy-bottom-grid .grid-text h3 {
  text-align: center;
  font-size: 35px;
  font-weight: 300;
  color: #003366;
  padding-bottom: 10px;
  text-transform: none;
  line-height: 1.1em;
}

.html-content-background .advocacy-bottom-grid .grid-text p {
  text-align: center;
  padding-bottom: 10px;
}
.html-content-background .advocacy-bottom-grid a {
  font-weight: 900;
  border-bottom: 1.5px solid #b9d9eb;
  text-transform: uppercase;
}

.html-content-background .advocacy-bottom-grid .grid-text small {
  color: #003366;
  font-size: 17px;
  font-weight: 400;
  line-height: 1.4;
  color: #333333;
  padding-bottom: 10px;
  margin: 0 !important;
}

.html-content-background .advocacy-bottom-grid .footer-text {
  padding-top: 50px;
  font-weight: 400;
  font-size: 17px;
  line-height: 24px;
}

.html-content-background .description--component .four-box {
  margin-bottom: 50px;
}
.field_full_html_paragraph .description--component .content-area {
  padding: 0px 50px;
}

.field_full_html_paragraph
  .description--component
  .content-area
  table.container
  td {
  font-size: 17px;
  color: #333333;
  line-height: 24px;
  font-weight: 400;
  padding: 16px 0 0 0;
  text-align: left;
  vertical-align: top;
}
.field_full_html_paragraph
  .description--component
  .content-area
  table.bottom48 {
  margin-bottom: 48px;
}
/*-------------Counter box section-------------------------*/
.description--component .counter-box h3 {
  font-size: 23px;
  line-height: 29px;
  font-weight: 600;
}
.description--component .counter-box .col-sm-2 {
  text-align: center;
}
.description--component .counter-box .col-sm-2 h1 {
  font-size: 60px;
  font-weight: 200;
  line-height: normal;
}
.description--component .counter-box .col-sm-2 span {
  color: #189cd7;
  font-size: 70px;
}
.description--component .counter-box p.text-center.update-month {
  margin-top: 30px;
}
.description--component .counter-box p em {
  color: #999999;
  font-size: 14px;
  font-weight: 400;
}
.paragraph.paragraph--type--body.paragraph-id--226 hr {
  border: 1px solid #979797;
}
.grants-html-section,
.grants-html-section,
.grants-html-section {
  margin: 34px auto;
}
.paragraph.paragraph--type--html-content-with-background.paragraph-id--213 {
  margin-top: 64px;
}
.paragraph.paragraph--type--body.paragraph-id--204 {
  margin-bottom: 64px;
}
.paragraph.paragraph--type--body.paragraph-id--204 a {
  border-bottom: 1.5px solid #b9d9eb;
  font-weight:900;
}
#dark-bg-banner a{
  font-weight:900;
}
.paragraph-id--263
  .paragraph-id--262
  .description--component
  .field--name-field-body
  ul {
  margin-top: 0;
}
.paragraph-id--435 .advocacy-bottom-grid .col-sm-3 {
  min-height: 466px !important;
}
.paragraph-id--533 #dark-bg-banner {
  padding: 64px 48px;
}
.paragraph.paragraph--type--body.paragraph-id--602 .row {
  display: flex;
  align-items: center;
  justify-content: center;
}
.paragraph.paragraph--type--html-content-with-background.paragraph-id--603 {
  margin-top: 0;
}
.paragraph.paragraph--type--_-column-card.paragraph-id--539 #two-column-card {
  padding-top: 0px;
}
.paragraph.paragraph--type--html-content-with-background.paragraph-id--605 {
  margin: 0px 0 64px 0px;
}
.paragraph.paragraph--type--video-with-content.paragraph-id--516 .text-content {
  padding: 0px 40px;
}
.paragraph-id--516 .whole-video-with-content-area {
  padding-top: 0px !important;
}
.paragraph--type--_-column-card.paragraph-id--527 #two-column-card {
  padding-top: 0px;
}
.paragraph-id--208 {
  margin: 64px 0px;
}
.paragraph.paragraph--type--body .img-wrapper {
  display: flex;
  justify-content: space-around;
  align-items: center;
  height: 245px;
}
.paragraph.paragraph--type--body .img-wrapper .award {
  text-align: center;
}
.paragraph-id--518 #full-html-content-background {
  margin-bottom: 0px !important;
  padding: 64px 0 32px 0;
}
.paragraph-id--518 #full-html-content-background h2 {
  margin-top: 0px !important;
}
p.primary-hyperoxaluria-full-html-background-img {
  margin-bottom: 16px;
}

.paragraph-id--1602 {
  margin-bottom: 0px !important;
}
#our-products .paragraph-id--1602 .image-desc-link .img-desc-link .img img {
  max-width: 230px;
}
.paragraph-id--530 p,
.paragraph-id--605 p {
  font-size: 14px !important;
}
.paragraph-id--530 a {
  font-weight: 400 !important;
}
.paragraph-id--161 h2 {
  margin-top: 0px;
}
.paragraph.paragraph--type--_-column-video-section.paragraph-id--473
  .three-column-video-content-box {
  padding-top: 16px;
}
.paragraph-id--482 h2 {
  margin-top: 0px !important;
}
.paragraph-id--489
  .field.field--name-field-description-text-area.field--type-text-long.field--label-hidden.field--item
  sup {
  top: 1px;
}
.paragraph-id--496 .patient-philosophy.corporate-responsibility {
  padding-top: 0px !important;
}
.paragraph-id--506 div.html-content-background h3 {
  padding-left: 5px;
}
.paragraph-id--501 h2 {
  margin-top: 0px !important;
}
.paragraph-id--46 p {
  margin-bottom: 0px !important;
}
.whole-full-html-callout-brochure-area p.margin-bottom-16px {
  margin-bottom: -30px !important;
}
.paragraph-id--177 h2 {
  margin-top: 0px !important;
}
.paragraph-id--177 ul {
  padding-left: 18px !important;
}
.paragraph-id--186 .banner-overlay-html-content-description--component ul {
  margin: 0px 0px 24px 0px;
}
.grants-html-section ul,
.grants-html-section  ul {
  margin: 0px 0px;
}
.paragraph-id--202 .banner-overlay-html-content-description--component {
  padding-bottom: 0px !important;
}
.paragraph-id--203 #dark-bg-banner {
  margin-bottom: 16px !important;
}
.paragraph-id--208 a {
  border-bottom: 1.5px solid #b9d9eb;
  font-weight:900;
}
.paragraph-id--207 #dark-bg-banner {
  /*   font-size: 23px;
    line-height: 32px; */
}
.paragraph-id--199 #light-bg-banner {
  margin-top: 0px !important;
}

.paragraph-id--317 .icon-copy-link-list-feilds {
  padding-bottom: 0px !important;
}
.paragraph-id--624 {
  padding-bottom: 64px !important;
}
.paragraph-id--624 p {
  margin: 0px !important;
  padding-left: 60px;
  font-size: 14px;
}

.paragraph-id--263 h2 {
  margin-top: 0px !important;
}
.paragraph-id--256 h2,
.paragraph-id--253 h2 {
  margin-top: 0px !important;
}
.paragraph-id--260 .field_fullhtml_light_dark_field {
  padding-top: 0px !important;
}
.paragraph-id--371 .link.our-products-ext a::after {
  content: "";
  background: url(../../images/External_link_font_awesome.svg.png);
  background-size: cover;
  width: 12px;
  height: 12px;
  display: block;
  position: absolute;
  top: 22px;
  right: -16px;
}

.paragraph-id--455 #accordion-column-content {
  padding-top: 0px !important;
}
.paragraph-id--455 #accordion-column-content h2 {
  margin-top: 0px !important;
  text-align: left;
}
.paragraph.paragraph--type--body.paragraph-id--398 {
  padding: 30px 0 64px;
}
.paragraph-id--384 .banner-overlay-html-content-description--component {
  padding-bottom: 12px !important;
}
.paragraph-id--387 #light-bg-banner {
  margin-bottom: 64px !important;
}
.paragraph-id--428 .button-more.button-more {
  padding: 15px 35px;
}
.paragraph-id--126 p.font-20,
.paragraph-id--93 p.font-20 {
  margin-bottom: 0px !important;
}
.paragraph-id--126 p.font-20.mb-32{
  margin-bottom:32px !important;
}
.bios-card-section > div > .field--item:last-child .bios-card-without-image-field {
  margin-bottom: 0;
}
.paragraph-id--66 p.font-20 {
  margin-bottom: 64px !important;
}
.grants-html-section  h3,
.grants-html-section h3,
.grants-html-section  h3,
.grants-html-section  h3 {
  margin-top: 0px !important;
}
.grants-html-section  ul,
.grants-html-section  ul,
.grants-html-section  ul,
.grants-html-section  ul {
  margin-bottom: 0px !important;
}
.paragraph-id--209 #light-bg-banner .field--name-field-link a,
.paragraph-id--210 #light-bg-banner .field--name-field-link a,
.paragraph-id--211 #light-bg-banner .field--name-field-link a {
  padding-left: 28px !important;
}
.paragraph-id--1184 h1.our-company::before {
  margin-left: -64px;
}
.paragraph-id--1184 h2.our-company::before {
  margin-left: -64px;
}
.flip-cards .flip-card {
  position: relative;
  text-align: center;
}
.flip-cards .flip-card div {
  color: white;
  position: absolute;
  height: 100%;
  width: 93%;
  top: 0;
  bottom: 0;
  left: 0;
  right: 0;

  transition: transform 0.4s, background-color 0.2s;
  transform-style: preserve-3d;
}
.flip-cards .flip-card .title {
  font-size: 35px;
  transform: rotateY(0deg);
}
.flip-cards .title strong {
  width: min-content;
  display: block;
  margin: 36% auto;
  font-weight: 600;
  line-height: 1;
}
.flip-cards .flip-card .desc {
  display: flex;
  align-items: center;
  padding: 10%;
  margin: 0 15px;
  background-color: transparent;
  transform: rotateY(90deg);
}
.flip-cards .flip-card .desc strong {
  font-weight: 600;
}
.flip-cards .flip-card:after {
  content: "";
  background-image: url(/themes/custom/alnylam/images/buttons-circle-open.svg);
  position: absolute;
  width: 40px;
  height: 40px;
  left: 45%;
  bottom: 24px;
  left: calc(50% - 20px);

  transform: rotate(0deg);
  transition: transform 0.3s;
}
.flip-cards .flip-card.flipped:after {
  transform: rotate(45deg);
}
.flip-cards .flip-card.flipped .title {
  transform: rotateY(90deg);
}
.flip-cards .flip-card.flipped .desc {
  transform: rotateY(0deg);
  background-color: rgb(0 51 102 / 85%);
}
.paragraph-id--517.paragraph--type--body .img-wrapper .award {
  flex: 0 0 20%;
  padding: 16px;
}
.paragraph-id--517 {
  padding-bottom: 16px;
}
.image-container.d-mobile {
  display: none;
}
@media (max-width: 767px) {
  .paragraph-id--1719 .newsList {
    padding: 0 !important;
  }
  .image-container {
    display: none;
  }
  .image-container.d-mobile {
    display: block;
  }
  .paragraph-id--1719 ul.newsList li {
    margin-right: 0 !important;
    background-size: 101px 101px;
    background-repeat: no-repeat;
    margin: 10px 0px !important;
    min-height: 104px;
    min-height: auto;
  }
  .paragraph-id--1719 .description--component {
    padding: 0 32px 0 16px;
  }
  .paragraph-id--1719 .description--component h2 {
    text-align: center;
    padding: 0 16px;
  }
  .paragraph-id--1720 .button-more.button-more {
    margin-top: 0 !important;
  }
  .paragraph-id--517.paragraph.paragraph--type--body .img-wrapper .award {
    flex: 0 0 50%;
    padding: 16px 0;
  }
  .paragraph-id--517.paragraph.paragraph--type--body .img-wrapper .award img {
    height: auto;
    width: auto;
    max-width:160px;
    margin-bottom: 0px;
  }
  .paragraph-id--518 #full-html-content-background {
    padding-top: 0 !important;
  }
  .paragraph-id--518 #full-html-content-background .text-align-center {
    text-align: center;
  }
  .paragraph-id--1721 .description--component {
    padding: 0;
  }
}
@media (min-width: 768px) and (max-width: 1000px) {
  .paragraph-id--518 #full-html-content-background {
    padding-top: 0 !important;
  }
  .paragraph-id--518 #full-html-content-background .text-align-center {
    text-align: center !important;
    margin-bottom: 32px !important;
  }
  .paragraph-id--517.paragraph.paragraph--type--body .img-wrapper .award {
    flex: 0 0 25% !important;
    padding: 16px 12px !important;
  }
  .paragraph-id--517.paragraph.paragraph--type--body .img-wrapper .award img {
    display: inline-block;
    height: auto;
    width: auto;
    margin-bottom: 0px;
  }
  .paragraph-id--1721 .description--component {
    padding: 0;
  }
  .paragraph-id--1719 .description--component h2.text-align-center {
    text-align: center;
  }

  .paragraph-id--1719 .newsList {
    display: flex;
    flex-wrap: nowrap;
    flex-direction: row;
  }
  .page-node-264 ul.newsList li {
    flex-grow: 1;
    flex-basis: 0;
    margin: 0 12px !important;
    padding: 0 !important;
    background-size: cover;
    background-position: unset;
  }
  .page-node-264 .newsList a {
    display: inline-flex !important;
    flex-direction: column !important;
    justify-content: flex-end !important;
    height: 210px !important;
    padding: 24px;
    text-decoration: none !important;
    background: rgba(0, 0, 0, 0.45) !important;
    background: -moz-linear-gradient(
      top,
      rgba(0, 0, 0, 0.3) 0%,
      rgba(0, 0, 0, 0.45) 100%
    ) !important;
    background: -webkit-linear-gradient(
      top,
      rgba(0, 0, 0, 0.3) 0%,
      rgba(0, 0, 0, 0.45) 100%
    ) !important;
    background: linear-gradient(
      to bottom,
      rgba(0, 0, 0, 0.3) 0%,
      rgba(0, 0, 0, 0.45) 100%
    ) !important;
    transition: padding 0.2s, background-color 0.2s !important;
    width: 100% !important;
    padding: 24px !important;
  }
  .page-node-264 .newsList a {
    background: rgba(0, 0, 0, 0.45) !important;
    background: -moz-linear-gradient(
      top,
      rgba(0, 0, 0, 0.3) 0%,
      rgba(0, 0, 0, 0.45) 100%
    ) !important;
    background: -webkit-linear-gradient(
      top,
      rgba(0, 0, 0, 0.3) 0%,
      rgba(0, 0, 0, 0.45) 100%
    ) !important;
    background: linear-gradient(
      to bottom,
      rgba(0, 0, 0, 0.3) 0%,
      rgba(0, 0, 0, 0.45) 100%
    ) !important;
  }
  .page-node-264 .newsList a .newsTitle {
    color: #fff;
  }
  .paragraph-id--1719 .newsList {
    padding: 0;
  }
  .paragraph-id--1720 .description--component .text-align-center {
    text-align: center;
  }
}
.paragraph-id--1698 .img-wrapper{
  height:auto !important;
}
.page-node-264 #full-html-content-background .award a {
  border-bottom: none;
}
#full-html-light-dark a{
  font-weight:900;
}