RNAi: A REVOLUTION IN BIOLOGY BUILT ON NOBEL PRIZE-WINNING RESEARCH
RNA interference (RNAi) is a breakthrough in understanding how genes are regulated in cells. It also represents a completely new approach to drug discovery and development. The 2006 Nobel Prize for Physiology or Medicine, awarded to Craig Mello and Andrew Fire, recognised the importance of RNAi as a major scientific discovery.
Our pipeline of investigational RNAi therapeutics is focused on diseases with high unmet medical need that fall under 4 Strategic Therapeutic Areas (STArs): genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.
Our products approved for patients in the European Union treat hereditary ATTR (hATTR) amyloidosis with polyneuropathy, acute hepatic porphyria (AHP), primary hyperoxaluria type 1 (PH1), and hypercholesterolemia. Our therapeutic product candidates in late-stage (Phase 2 – Phase 3) development focus on hereditary ATTR (hATTR) amyloidosis, haemophilia and rare bleeding disorders and complement-mediated diseases. We have a number of early-stage programmes in development.
JOIN OUR TEAM
As we pursue our goal of becoming a commercial organization that can independently deliver medicines to patients, we are seeking individuals with diverse skills, experiences, and backgrounds to help us build a world-class team. We are based in Cambridge, USA, with offices in Zug, Switzerland, and Maidenhead, UK, but we are also hiring throughout Europe.
Alnylam UK Ltd.
Braywick Gate, Braywick Road, Maidenhead, Berkshire SL6 1DA
LEARN MORE ABOUT ALNYLAM
In-depth information about our science, our pipeline, resources for medical professionals and patients, and the latest news about Alnylam.
To see a list of the UK patient organizations that Alnylam supported in 2018, please click here; for 2019, please click here; for 2020, please click here, for 2021, please click here and for 2022, please click here.
View the Executive Summary for the Joint Working Agreement between Alnylam UK and University Hospital Birmingham here.
View the Executive Summary for the Joint Working Agreement between Alnylam UK and National Amyloidosis Centre here.
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Alnylam UK Ltd.
Date of prep: June 2023
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