Management Board

Alnylam has assembled a team of passionate leaders from the biopharmaceutical industry, bringing together their experiences of drug discovery, drug development, and commercialization. All members of the Management Board are also part of the Operating Team.

John Maraganore, PhD

Chief Executive Officer

Since 2002, Dr. John Maraganore has served as the CEO and a Director of Alnylam.

Prior to Alnylam, Dr. Maraganore served as an officer and a member of the management team for Millennium Pharmaceuticals, Inc. As Senior Vice President, Strategic Product Development for Millennium, he was responsible for the company’s product franchises in oncology, and cardiovascular, inflammatory, and metabolic diseases. He was previously Vice President, Strategic Planning and M&A and, prior to that, he was General Manager of Millennium BioTherapeutics, Inc., a former subsidiary of Millennium. Before Millennium he served as Director of Molecular Biology and Director of Market and Business Development at Biogen, Inc. At Biogen, Dr. Maraganore invented and led the discovery and development of ANGIOMAX® (bivalirudin) for injection, formerly HIRULOGTM and currently marketed by The Medicines Company. Prior to Biogen, Dr. Maraganore was a scientist at ZymoGenetics, Inc., and the Upjohn Company.

Dr. Maraganore received his MS and PhD in biochemistry and molecular biology at the University of Chicago. He is the Chair of the Board for Agios Pharmaceuticals. Dr. Maraganore is Chair of the Biotechnology Industry Organization (BIO) Board, and is a member of the BIO Executive Committee.

Barry Greene


Barry Greene joined Alnylam in 2003 and has more than 25 years of experience in healthcare, pharmaceutical, and biotechnology industries.

Prior to Alnylam, Barry was General Manager of Oncology at Millennium Pharmaceuticals, Inc., where he led the company’s global strategy and execution for its oncology business, including strategic business direction and execution, culminating in the successful approval and launch of VELCADE® (bortezomib) in mid-2003. Prior to joining Millennium in February 2001, Barry served as Executive Vice President and Chief Business Officer for Mediconsult.com. Preceding that, Barry’s past experiences include Vice President of Marketing and Customer Services for AstraZeneca, formerly AstraMerck; Vice President Strategic Integration with responsibility for the AstraZeneca North American post-merger integration; and Partner, Andersen Consulting, responsible for the pharmaceutical/biotechnology marketing and sales practice.

Barry received his BS degree in Industrial Engineering from University of Pittsburgh and served as Senior Scholar at Duke University, Fuqua School of Business. Barry also serves on the Boards of Acorda Therapeutics and Karyopharm Therapeutics.

Yvonne Greenstreet, MBChB, MBA

Chief Operating Officer

Dr. Yvonne Greenstreet possesses 25 years of global experience in the pharmaceutical industry, where she has been in senior roles in research and development, strategy, and portfolio management. She has successfully led product development and commercialization teams in a wide range of therapy areas, bringing new medicines to patients.

Yvonne was previously Senior Vice President and Head of Medicines Development at Pfizer, and a member of the executive team for the specialty business, with accountability for a portfolio that included the immuno-inflammation, vaccine, specialty neuroscience, and rare disease areas. Prior to Pfizer, Yvonne held roles of increasing responsibility at GlaxoSmithKline, including Senior Vice President and Chief of Strategy for Research and Development, Senior Vice President for Medicines Development and Chief Medical Officer for Europe.

Yvonne received her medical degree (MBChB) from the University of Leeds, UK, and an MBA degree from INSEAD, France. She serves as a member of the board of directors of Pacira Pharmaceuticals, Inc., a specialty pharmaceutical company, and Indivior PLC, a global specialty pharmaceutical business. Dr. Greenstreet also serves on the Scientific Advisory Committee of the Bill and Melinda Gates Foundation.

Pushkal Garg, MD

Chief Medical Officer

Dr. Pushkal Garg joined Alnylam in 2014 with 15 years of experience in clinical drug development. He oversees clinical research & operations, biometrics & data management, and medical writing groups.

Prior to joining Alnylam, Dr. Garg served as Vice President, Global Clinical Research, Immunoscience at Bristol-Myers Squibb (BMS). He was the strategic leader of the Immunoscience franchise and successful developer of multiple clinical assets across the areas of rheumatology, gastroenterology, nephrology, and transplantation. While at BMS, he was instrumental to the late-stage development and approval of Nulojix® (belatacept) for kidney transplant recipients, and for supplementary biologics license applications (BLAs) for Orencia® (abatacept). Preceding this, Dr. Garg held various roles at Millenium Pharmaceuticals, overseeing the clinical development of multiple small molecule and biologic therapeutics for the treatment of inflammatory disorders.

Dr. Garg received a Bachelor of Arts with high honors in Biochemistry from the University of California, Berkeley, and a medical degree from the University of California, San Francisco. He completed residency training in Internal Medicine at UCSF, was a fellow in the Robert Wood Johnson Clinical Scholars Program at Johns Hopkins University, and served on the faculty of Harvard Medical School and the Brigham & Women’s Hospital in Boston prior to joining the industry. Dr. Garg is a member of the Board of Directors of SQZ Biotechnologies (SQZ).

Laurie Keating, JD


Laurie Bartlett Keating joined Alnylam in 2014 with more than 25 years of executive experience at high technology and biotechnology companies.

Prior to joining Alnylam, Laurie served as Senior Vice President, General Counsel and Secretary of Millennium: The Takeda Oncology Company for 9 years, responsible for setting the company’s global legal, intellectual property, and corporate quality strategies and priorities. Prior to Millennium, Laurie was co-founder and the first CEO of Hydra Biosciences, Inc. Before co-founding Hydra, she served as an executive at high-growth technology companies, including Iomega Corporation, and Sybase, Inc., a software company that grew from a few hundred to 6,000 employees during Laurie’s tenure on the management team. Based on her leadership at Sybase, Laurie was named one of the 45 most influential in-house lawyers in the United States under the age of 45. Upon graduating from law school, Laurie practiced law at McCutchen, Doyle, Brown and Enersen (now Bingham McCutchen) in San Francisco.

She has a Doctor of Jurisprudence degree from the University of California, Hastings College of the Law, and a BA in Economics from the University of California at Berkeley. Laurie is a member of the Board of Directors of MassBio, and a past chair of the BIO General Counsels Committee.



Dr. Saraswathy (Sara) Nochur joined Alnylam in 2006 as the Vice President of Regulatory Affairs, and also held roles as Program Leader for 2 late-stage programs. She was promoted to Senior Vice President in 2012, and also had Quality Assurance reporting to her. During her time at Alnylam, she has been instrumental in the clinical evaluation of a number of different drug RNAi candidates and in building the Regulatory teams in the United States. and Europe, comprising overall regulatory strategy, CMC strategy, regulatory operations, and Ad-Promo/labeling. Dr. Nochur is an executive co-sponsor (along with Barry Greene) of Alnylam’s Diversity & Inclusion initiative.

Dr. Nochur has been in the biotechnology industry since 1989. Prior to Alnylam, she held the position of Vice President, Regulatory Affairs at The Medicines Company. Before her 4 years there, Dr. Nochur served as Director, Product Development and Regulatory Affairs for CereMedix, Inc. She also held senior positions at BioTrack, Inc. Dr. Nochur started her career as a scientist at DynaGen, Inc., and worked on regulatory submissions for in vitro diagnostics as well as drugs, culminating in the role of Director, New Product Development.

Dr. Nochur received her BS and MS degrees in Microbiology from the University of Bombay in India, and her PhD in Biochemical Engineering at the Massachusetts Institute of Technology.

Manmeet S. Soni

Chief Financial Officer

Manmeet Soni joined Alnylam in May 2017. He provides strategic leadership over all financial management company-wide, including the global finance, investor relations, and communications teams.

Prior to joining Alnylam, Manmeet served as Chief Financial Officer and Treasurer of ARIAD Pharmaceuticals, Inc., where he played a central role in the strategic review, turnaround, and subsequent acquisition of ARIAD Pharmaceuticals, Inc. by Takeda Pharmaceuticals Company Limited. Before joining ARIAD Pharmaceuticals, Inc., Manmeet worked at Pharmacyclics, Inc., where he served most recently as Chief Financial Officer and Treasurer. He also played a vital role in the acquisition of Pharmacyclics, Inc. by Abbvie, Inc. for $21 billion. Previously, Manmeet worked at ZELTIQ Aesthetics Inc., and PricewaterhouseCoopers San Jose, in the Life Science and Venture Capital Group. Prior to that, he worked at PricewaterhouseCoopers India.

Manmeet is currently a board member and audit committee chair at Pulse Biosciences and a board member and audit committee member at Arena Pharmaceuticals, Inc. He graduated from Hansraj College at Delhi University in India. He is a Certified Public Accountant, licensed in the state of California, and a Chartered Accountant from India.

Akshay Vaishnaw, MD, PhD

PRESIDENT, Research & Development

Dr. Akshay Vaishnaw joined Alnylam in 2006, coming from Biogen, Inc., where he was most recently Senior Director, Translational Medicine.

In his 7 years at Biogen, Dr. Vaishnaw was involved in many aspects of clinical research and business development, and led the effort for the approval of AMEVIVE® (alefacept) for psoriasis.

Dr. Vaishnaw received his MD from the University of Wales College of Medicine, UK, and his PhD from the University of London, UK, in Molecular Immunology. He is a Fellow of the Royal College of Physicians, UK. Dr. Vaishnaw is a member of the Board of Directors for Scholar Rock and for Editas Medicine. In addition, he has published papers in leading scientific journals and authored several textbook chapters relating to autoimmune disease.

Kelley Boucher


Kelley Boucher joined Alnylam in 2019 bringing nearly 20 years of experience within the biotechnology and medical device industries. She oversees the global HR organization which includes talent planning & strategy, organizational effectiveness, talent acquisition, learning & development, total rewards, and HR systems.

Prior to Alnylam, Kelley served as Vice President and Global Head of Human Resources at Abiomed for three years as the company experienced exponential growth and commercial execution. Before her time at Abiomed, Kelley spent 10 years at Shire where she held a variety of roles across HR, eventually becoming Vice President and Head of Human Resources for Technical Operations and then Shire’s Corporate Divisions. She also managed the organizational design component of multiple acquisitions. Prior to Shire, Kelley was a Principal Consultant at Clockwork Consulting (a pharmaceutical recruitment firm) and worked at Syntonix Pharmaceuticals (acquired by Biogen) and Digitas. She was honored with the Healthcare Business Women’s Association Rising Star award in 2013. Kelley is a member of the Healthcare Business Women’s Association (HBA), the Human Resources Leadership Forum (HRLF) and the Corporate Executive Board (CEB).

Kelley attended Cornell University where she received her Bachelor of Arts in government relations and the Darden School of Business at the University of Virginia where she completed her studies in the Strategic Leadership Development executive program.

Board of Directors

The Alnylam Board of Directors is composed of accomplished leaders from the healthcare industry who bring their experience in science, drug development, commercialization, and strategy to our efforts in developing RNAi (RNA interference) therapeutics.

Michael W. Bonney


Chief Executive Officer and Chair of Kaleido Biosciences; former Partner of Third Rock Ventures; former Chief Executive Officer and Director of Cubist Pharmaceuticals; Trustee of the Tekla complex of life sciences– and healthcare–dedicated funds; Director of Celgene Corporation and Sarepta Therapeutics.

Dennis A. Ausiello, MD

Director of the Center for Assessment Technology and Continuous Health (CATCH); Jackson Distinguished Professor of Clinical Medicine at Harvard Medical School; Physician‐in‐Chief Emeritus at Massachusetts General Hospital; Member of the Institute of Medicine of the National Academy of Sciences and the American Academy of Arts and Sciences; Director of Pfizer and Seres Therapeutics.

Marsha H. Fanucci

Former Chief Financial Officer of Millennium Pharmaceuticals; Director of Ironwood Pharmaceuticals and Syros Pharmaceuticals.

Margaret A. Hamburg, MD

Former Commissioner of the U.S. Food & Drug Administration (FDA); Foreign Secretary of the National Academy of Medicine (NAM); President-elect of the American Association for the Advancement of Science (AAAS).

John M. Maraganore, PhD

Chief Executive Officer of Alnylam; Chair of the Board of Directors of Agios Pharmaceuticals; Chair of the Biotechnology Industry Organization (BIO).

Steven M. Paul, MD

Chairman of the Board, President and Chief Executive Officer of Karuna Therapeutics and board member of Voyager Therapeutics, Inc.; Venture Partner at Third Rock Ventures; co-founder and board member of SAGE Therapeutics; trustee for the Foundation for the National Institute of Mental Health (NIH); former President of the Lilly Research Laboratories of Eli Lilly and Company; former Scientific Director of the National Institute of Mental Health and adjunct professor of Psychiatry at Washington University of St. Louis School of Medicine.

David E.I. Pyott

Former Chair and Chief Executive Officer of Allergan; Lead Director of Avery Dennison Corporation; Member of the Supervisory Board of Royal Philips in the Netherlands; Director of BioMarin Pharmaceuticals.

Colleen Reitan

Former President of Plan Operations and Chief Operating Officer of Health Care Service Corporation (HCSC); former President and Chief Operating Officer of Blue Cross Blue Shield of Minnesota.

Paul R. Schimmel, PhD

Ernest and Jean Hahn Professor of Molecular Biology and Chemistry and Faculty Member of the Skaggs Institute for Chemical Biology at the Scripps Research Institute; Founder of Alnylam; Member of the National Academy of Sciences, the Institute of Medicine, the American Philosophical Society, the National Academy of Inventors, and the American Academy of Arts and Sciences; Co-founder of Cubist Pharmaceuticals, Alkermes, and Repligen; Director of aTyr Pharma and Tocagen.

Amy W. Schulman, JD

Co-founder, Chief Executive Officer, and Director of Lyndra; Chief Executive Officer of Olivo Labs; Executive Chair of SQZ Biotech and Suono Bio; Senior Lecturer at Harvard Business School; former Executive Vice President and General Counsel of Pfizer; served as the Business Unit Lead for Pfizer Consumer Healthcare; Director of Blue Buffalo Pet Products, Ironwood Pharmaceuticals, and Arsanis.

Phillip A. Sharp, PhD

Institute Professor, The Koch Institute for Integrative Cancer Research, MIT; Founding Director of McGovern Institute for Brain Research, MIT; Nobel Laureate; Founder of Alnylam; Co-founder and former Director of Biogen; Member of the National Academy of Sciences, the Institute of Medicine, and the American Academy of Arts and Sciences; Director of Syros Pharmaceuticals.


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